Cancerfighter’s Weblog

Alternative cancer therapies and ideas

pancreatic cancer cures?

Posted by Jonathan Chamberlain on December 30, 2009

Cancer: The Complete Recovery Guide

Cancer Recovery Guide: 15 Alternative and Complementary Strategies for Restoring Health

For details go to

“This book tells me everything. Why didn’t my doctor tell me this?” – Rev. Bill Newbern


Revisiting the ALA/N (-Lipoic Acid/Low-Dose Naltrexone) Protocol for People With Metastatic and Nonmetastatic Pancreatic Cancer: A Report of 3 New Cases
Burton M. Berkson, MD, MS, PhD
The Integrative Medical Center of New Mexico, Las Cruces, NM, USA, New Mexico State University, Las Cruces, NM, USA

Daniel M. Rubin, ND, FABNO

Southwest College of Naturopathic Physicians, Scottsdale, AZ, USA, rubin@naturopathics pecialists. com

Arthur J. Berkson, MD

The Integrative Medical Center of New Mexico, Las Cruces, NM, USA

The authors, in a previous article, described the long-term survival of a man with pancreatic cancer and metastases to the liver, treated with intravenous alpha-lipoic acid and oral low-dose naltrexone (ALA/N) without any adverse effects. He is alive and well 78 months after initial presentation. Three additional pancreatic cancer case studies are presented in this article. At the time of this writing, the first patient, GB, is alive and well 39 months after presenting with adenocarcinoma of the pancreas with metastases to the liver. The second patient, JK, who presented to the clinic with the same diagnosis was treated with the ALA/N protocol and after 5 months of therapy, PET scan demonstrated no evidence of disease. The third patient, RC, in addition to his pancreatic cancer with liver and retroperitoneal metastases, has a history of B-cell lymphoma and prostate adenocarcinoma. After 4 months of the ALA/N protocol his PET scan demonstrated no signs of cancer. In this article, the authors discuss the poly activity of ALA: as an agent that reduces oxidative stress, its ability to stabilize NFkB, its ability to stimulate pro-oxidant apoptosic activity, and its discriminative ability to discourage the proliferation of malignant cells. In addition, the ability of lowdose naltrexone to modulate an endogenous immune response is discussed. This is the second article published on the ALA/N protocol and the authors believe the protocol warrants clinical trial.

Key Words: pancreatic cancer • naltrexone • low-dose naltrexone • LDN • ALA/N • -lipoic acid • NF B • nuclear factor B • antioxidant • gemcitabine

Integrative Cancer Therapies, Vol. 8, No. 4, 416-422 (2009)

Note: The Cancer Survivor’s Bible (2012) is now available – see

“Jonathan, I bought your books. They are excellent and should be on every list of recommended cancer resources.”

I: 10.1177/15347354093 52082



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