Cancerfighter’s Weblog

Alternative cancer therapies and ideas

How effective is chemo in fighting cancer?

Posted by Jonathan Chamberlain on August 15, 2012


 

Here is a link to a very important analysis as to how effective chemotherapy is

The Contribution of Cytotoxic Chemotherapy
to 5-year Survival in Adult Malignancies

Graeme Morgan*, Robyn Wardy, Michael Bartonz
*Department of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore
Hospital, Sydney, NSW; yDepartment of Medical Oncology,
St Vincent’s Hospital, Sydney, NSW; zCollaboration for Cancer
Outcomes Research and Evaluation, Liverpool Health Service, Sydney, NSW, Australia
ABSTRACT:
Aims: The debate on the funding and availability of cytotoxic drugs raises questions about the contribution of curative or adjuvant cytotoxic chemotherapy to survival in adult cancer patients. Materials and methods: We undertook a literature search for randomised clinical trials reporting a 5-year survival benefit attributable solely to cytotoxic chemotherapy in adult malignancies. The total number of newly diagnosed cancer patients for 22 major adult
malignancies was determined from cancer registry data in Australia and from the Surveillance Epidemiology and End Results data in the USA for 1998. For each malignancy, the absolute number to benefit was the product of (a) the total number of persons with that malignancy; (b) the proportion or subgroup(s) of that malignancy showing a benefit; and (c) the percentage increase in 5-year survival due solely to cytotoxic chemotherapy. The overall contribution was the sum total of the absolute numbers showing a 5-year survival benefit expressed as a percentage of the total number for the 22 malignancies.
Results:

The overall contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults was estimated to be 2.3% in Australia and 2.1% in the USA.
Conclusion:

As the 5-year relative survival rate for cancer in Australia is now over 60%, it is clear that cytotoxic chemotherapy only makes a minor contribution to cancer survival. To justify the continued funding and availability of drugs used in cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required.

Morgan, G. et al. (2004). Clinical Oncology 16, 549e560
 2004 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

http://www.burtongoldberg.com/home/burtongoldberg/contribution-of-chemotherapy-to-five-year-survival-rate-morgan.pdf

The Cancer Survivor’s Bible – 550 pages of facts, discussion and options – see www.fightingcancer.com for details

“This is the book everyone with cancer needs to read.” ; “Inspirational”

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